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About This Drill
AP Biology — Unit 2 — Membrane Permeability — Drill 6 is a practice drill. It contains 5 original questions created by Brian Stewart, a Barron's test prep author with over 20 years of tutoring experience.
Practice analyzing membrane permeability and selective transport across phospholipid bilayers with this AP Biology drill.
Passage
The plasma membrane is selectively permeable, allowing some substances to cross freely while restricting others. Small, nonpolar molecules such as O2 and CO2 diffuse directly through the phospholipid bilayer. Small uncharged polar molecules such as water can diffuse slowly but cross much more efficiently via aquaporin channels. Large polar molecules and ions, however, cannot cross without the assistance of transport proteins.
A student conducts an experiment to investigate the permeability of artificial phospholipid bilayers (liposomes) to four different solutes. Each liposome preparation is identical in composition. The student measures the rate of solute movement across each liposome membrane over 30 minutes and records the results below.
Solute Molecular Size Polarity Relative Transport Rate
CO2 Small Nonpolar High
Glucose Large Polar Very Low
Na+ Small Charged (ion) Negligible
Ethanol Small Amphipathic (partially polar) Moderate-High
Questions in This Drill
- Based on the data in the table, which of the following best explains why Na+ has a negligible transport rate across the liposome membrane?
- A student argues: "Because ethanol has a partially polar character, it should be completely excluded from crossing the liposome membrane, similar to glucose." Which of the following best identifies the flaw in this argument?
- The student proposes that if aquaporin channel proteins were inserted into the liposome membranes, the transport rate of water would increase but the transport rate of Na+ would remain negligible. Which of the following best evaluates this prediction?
- Which of the following changes to the experimental design would best allow the student to determine whether a transport protein is required for glucose to cross the membrane at a significant rate?
- A researcher claims that the data in the table are sufficient to conclude that cell membranes in living organisms use only passive transport mechanisms. Which of the following best identifies the limitation of this claim?